Company Overview
CRISPR Therapeutics is a leading gene editing company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. CRISPR/Cas9 is a revolutionary gene editing technology that allows for precise, directed changes to genomic DNA. CRISPR Therapeutics has established a portfolio of therapeutic programs across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine, and rare diseases. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic collaborations with leading companies including Bayer, Vertex Pharmaceuticals and ViaCyte, Inc. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Cambridge, Massachusetts, and business offices in San Francisco, California and London, United Kingdom.
Job Summary
We are seeking an Engineer to join the Cell Process Development group at CRISPR Therapeutics. Successful candidate will aid in performing and analyzing experiments for multiple preclinical and clinical genetically modified cellular products to support Immuno-Oncology programs. Candidates with enthusiasm, passion, and a desire to create important new medicines for patients are highly favorable.
Responsibilities
Work with Process Development to generate and analyze process development data to develop an understanding of cellular product critical quality attributes to guide testing and process control strategies.
Develop data sets supporting product specification and for qualification and/or validation of cell-based assays at CMOs and GMP test labs.
Develop methods to analyze in-process samples to better understand process parameters.
Maintain clear and complete experimental records
Analyze and present experimental data.
Author technical reports of assay development/optimization.
Minimum Qualifications
BS in Chemical/Biochemical Engineering or related discipline with 2+ years of relevant experience or MS
Hands-on experience with molecular and cellular biology techniques.
Ability to work independently as well as part of a team and collaborate with cross-functional groups.
Excellent oral and written communication skills.
Highly organized with significant attention to details.
Preferred Qualifications
Experience with flow cytometry and molecular biology assays.
Experience in immune-oncology and/or T cell biology.
Experience using Quality by Design (QbD), filing IND applications, or experience in tech transfer is a plus.
DoE experience and the ability to use statistical programs such as JMP or Minitab.
Process or analytical development experience.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy
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